Down syndrome, autism, epilepsy, dwarfism, goiter, blindness and numerous pathologies extremely concentrated in one region of Java.
The causes that led to the beginning of this extraordinary case were, among others, a food crisis that deprived the people of the basic element of their diet, rice. A plague of rats wiped out with all crops, which made for 4 years people base their diet on the consumption of leaves and roots of banana with a lack of nutrients. Therefore, all pregnant women in this period could not feed their fetuses casing a lot of anomalies in their births.
This reason, along with the genetic component, inbreeding and poverty make this are have a percentage of people with disabilities much higher than usual.